The most common side effects of Oral Semaglutide are gastrointestinal and may include nausea, vomiting, diarrhea, constipation, abdominal discomfort, decreased appetite, bloating, and indigestion. These effects are often more noticeable when treatment is first started or when the dose is increased.
More serious side effects are less common but may include pancreatitis, gallbladder problems, dehydration, kidney problems, severe gastrointestinal symptoms, allergic reactions, and low blood sugar when used with certain diabetes medications.
Semaglutide also carries a warning regarding the potential risk of thyroid C-cell tumors and may not be appropriate for individuals with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2. A healthcare provider should review your medical history before treatment.